NFL Week 5 predictions

NFL Week 5 Predictions 2026: Picks & Scores for Every Game (Oct 8-12)

by

NFL Week 5 predictions: Cowboys, the Bengals, and the Texans as the safer bets. I also have the Falcons down for the upset pick. Week 5 runs across 15 games. They start on Thursday, October 8, and go through Monday, October 12. This week also marks the first byes of the season. Below you will find every matchup. Each one includes a predicted score, the odds, and what to watch most in that game.

NFL Week 5 Predictions: Our Picks and Scores

GameLineOur pick
Buccaneers at Cowboys (Thursday)DAL -9.5 to -10Cowboys 31, Buccaneers 20
Eagles vs Jaguars (London)JAX -4.5 to -5.5Jaguars 24, Eagles 17
Bears at PackersCHI -2.5 to -3Bears 27, Packers 23
Bengals at DolphinsCIN -7.5Bengals 27, Dolphins 17
Browns at JetsNYJ -1.5 to -2.5Jets 20, Browns 17
Texans at TitansHOU -6.5 to -7Texans 24, Titans 14
Colts at SteelersPIT -2.5Steelers 23, Colts 20
Raiders at PatriotsNE -3.5Patriots 27, Raiders 20
Vikings at SaintsMIN -1.5 to -2.5Vikings 24, Saints 20
Giants at CommandersWAS -2.5 to -3.5Commanders 27, Giants 21
Broncos at ChargersDEN -2.5 to -3.5Broncos 23, Chargers 20
Lions at CardinalsDET -4.5 to -5.5Lions 31, Cardinals 27
49ers at SeahawksSEA -2.5 to -3Seahawks 27, 49ers 24
Ravens at Falcons (Sunday night)BAL -3.5Falcons 27, Ravens 24 (upset)
Bills at Rams (Monday night)LAR -2.5Rams 30, Bills 27

Lines are consensus ranges from midweek and will move. These are our opinions, not betting advice, so check a sportsbook for current prices.

NFL Week 5 Odds: Biggest Favorites

  • Cowboys over Buccaneers: About 83% to win on prediction markets. Dallas has scored 30 or more in three straight games, and Tampa Bay is starting a backup quarterback. Read our full Cowboys vs Buccaneers prediction.
  • Bengals over Dolphins: About 77% to win, and SportsLine’s computer model backs Cincinnati.
  • Texans over Titans: About 73% to win. Houston is 0-4 and desperate, and Covers lists the Texans at -6.5 as a bet to make early.

NFL Week 5 Predictions: Closest Games

  • Bears at Packers: Chicago’s balanced offense averages 28.0 points per game, and Green Bay’s depleted front is allowing 4.9 yards per carry between the tackles. We side with the Bears.
  • Vikings at Saints: The Saints just lost 45-24 to the Falcons, so New Orleans is in a tough spot even at home.
  • Raiders at Patriots: New England just stunned the Bills 29-26 in Buffalo, and the Patriots are favored by 3.5 at home.
  • 49ers at Seahawks: A divisional game with a field-goal spread, and Seattle holds the home edge.

Upset Pick of the Week: Falcons Over Ravens

Atlanta scored 45 points in a blowout of New Orleans on Monday night and is home on Sunday night against Baltimore. Ravens money is steady, with Baltimore about -3.5 and a roughly 62% win probability on prediction markets, but the Falcons’ offense is hot and their defense has been solid against the run. We like Atlanta to win a tight game. See our Falcons vs Saints prediction for how Atlanta got here.

Games to Watch

  • Thursday Night Football: Buccaneers at Cowboys, 8:15 PM ET on Prime Video.
  • Sunday Night Football: Ravens at Falcons.
  • Monday Night Football: Bills at Rams, 8:15 PM ET on ESPN and ABC at SoFi Stadium.
  • London game: Eagles vs Jaguars is the early Sunday kickoff.

NFL Week 5 Predictions FAQ

What are the best NFL Week 5 predictions?

Our safest picks are the Cowboys, Bengals and Texans. Our upset pick is the Falcons over the Ravens on Sunday night.

Which games are on Thursday, Sunday night and Monday night?

Thursday is Buccaneers at Cowboys, Sunday night is Ravens at Falcons, and Monday night is Bills at Rams.

How many games are in NFL Week 5?

There are 15 games, because the first bye weeks begin in Week 5.

Who is the biggest favorite in Week 5?

The Cowboys, at roughly 9.5 to 10 points over the Buccaneers.

Odds come from Covers and Yahoo Sports.

Your take: Which Week 5 game gets the biggest upset, and what is your perfect-week record so far? Tell us in the comments.

Leave a Comment